The Course of Empire then is a compendium of various and sometimes quite different national interests. Utilizing a chronological, fill in the blank approach, DeVoto literally fills in the map of North America as viewed, rightly or wrongly, by each succeeding explorer. Chapter by chapter this story unfolds across the entire history of North American exploration. Thus, the reader meets everyone in chronological sequence, starting with Balboa and ending with Lewis and Clark.
Since subsequent explorers often had access to the records of those that preceded them, DeVoto is not only able to fill in the North American map with the contribution of each exploration, he is also able to link each exploration to its fundamental drivers: national intent and economic interest. As a result, he is able to underscore the ebb and flow of New World power as each country's global interests and economic situation changed over time.
For example, Spain's 16th century interest was mostly focused on conquest and plunder. As a result, Spain's more northern explorations, led by De Soto and Coronado, were limited by the lack exploitable civilizations. In contrast, after the defeat of the Spanish Armada and Spain's decline as a world power, England's subsequent 17th and 18th century efforts were more driven by land acquisition, sugar and the fur trade. It is easy to see why then that the French and Indian War was fought and why Britain's explorations are so much more consistent and focused on such dramatically different sections of North America.
Of critical interest is how the author weaves the unbelievable scope of this effort into a consistent whole, telling the story of how the geography of North America limited and encouraged continental expansion and ultimately defined the national borders of the United States. This is an excellent work and well worth your time.