book: Effects of alcoholism, anxiety and depression on P300 in women: a pilot study...

book: Effects of alcoholism, anxiety and depression on P300 in women: a pilot study *.(Statistical Data Included): ... | Lance O. Bauer, Laura Costa, ...

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	*Effects of alcoholism, anxiety and depression on P300 in women: a pilot study .(Statistical Data Included): ...** Lance O. Bauer, Laura Costa, ... Alcohol Research Documentation, Inc., 2001
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This digital document is an article from Journal of Studies on Alcohol, published by Alcohol Research Documentation, Inc. on September 1, 2001. The length of the article is 5123 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: Objective: The present investigation was designed for the purpose of revealing functional brain impairments associated with alcoholism, anxiety and depression. Method: The subjects were 56 women, with an average (SD) age of 34.8 (7.3) years. None reported a history of neurological or major medical disorders, or drug abuse. Twenty-nine of the women met DSM-IV lifetime criteria for a diagnosis of alcohol abuse or dependence. Twenty-five women reported mild or higher levels of anxiety, as indexed by a Beck Anxiety Inventory (BAI) score greater than 7. Electroencephalographic activity was recorded while subjects performed a visual ("oddball") selective attention task comprised of rare target, rare nontarget and frequent nontarget stimuli. P300 event-related potentials elicited by the rare target and rare nontarget stimuli were analyzed. Results: The initial analysis was structured as a 2 (alcoholism) by 2 (anxiety) factorial. Analyses revealed no significant effects of alcoholism on P300. However, women reporting a BAI score greater than 7 exhibited significantly smaller P300 amplitudes than their non-anxious counterparts. The P300 decrement remained significant when depression level (Beck Depression Inventory [BDI-II]) and age were entered as covariates. A separate analysis was conducted in which the 56 subjects were classified by alcoholism and depression level (BDI-II score [less than or equal to] 13 vs > 13). The analysis revealed no significant P300 differences associated with these factors. Conclusions: It is hypothesized that anxiety might play a role in mediating or amplifying the P300 decrements that have been attributed to alcoholism and depression in women. Additional and more comprehensive studies are needed to discern the validity of this hypothesis. (J. Stud. Alcohol 62: 571-579, 2001)

Citation Details
Title: Effects of alcoholism, anxiety and depression on P300 in women: a pilot study *.(Statistical Data Included)
Author: Lance O. Bauer
Publication: Journal of Studies on Alcohol (Refereed)
Date: September 1, 2001
Publisher: Alcohol Research Documentation, Inc.
Volume: 62 Issue: 5 Page: 571(9)

Article Type: Statistical Data Included

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