This book is written primarily from a Unites States Vs Native American perspective. However, it acknowledges US, British, French, Spanish, and Mexican interactions, all of which treated the American Indian in much the same way: Make them dependent on foreign technology, guns, powder, fabric, iron, food, transportation, etc., and use that dependence against them.
All European influences exploited inter tribal differences, hatreds and animosities, fighting the American theater of European wars with Indians against Indians. All introduced diseases and some utilized germ warfare in defeating their Native American enemies. From the outset in 1492 the result was a foregone conclusion: Native Americans would be annihilated.
This is the story of how it happened.